By Schedule




CARDIAC SURGERY FORUM SESSION

07:00 a.m.
Posterior Mitral Leaflet Extension: A New Adjunctive
Repair Option for Ischemic Mitral Regurgitation?
Speaker(s): Frank Langer, Filiberto Rodriguez, Allen Cheng, Saskia Ortiz, Mary K Zasio, David Liang, George T Daughters, Neil B Ingels, D Craig Miller; Stanford, CA, Palo Alto, CADiscussant: Robert C. Gorman

07:12 a.m.
Magnesium as a Neuroprotectant in Cardiac Surgery: A Randomized Study
Speaker(s): Sunil K Bhudia, Delos M Cosgrove, Richard I Naugle, Jeevanantham Rajeswaran, Buu-khanh Lam, Emily Walton, Roberta C Palumbo, Eugene H Blackstone; Cleveland, OHDiscussant: Ralph J. Damiano, Jr.

07:24 a.m.
Electroporation Mediated Interleukin-10 Overexpression in Skeletal Muscle Reduces Acute Rejection in Rat Cardiac Allografts
Speaker(s): Reza Tavakoli, Amiq Gazdhar, Jaroslaw Pierog, Anna Bagdannova, Matthias Gugger, Steven C Hyde, Michele Genoni, Ralph A Schmid; Zurich, Switzerland, Bern, Switzerland, Oxford, UKDiscussant: Joren C. Madsen

07:36 a.m.
Myocardial Protection Using An Omega-3 Fatty Acid Infusion: Quantification And Mechanism Of Action
Speaker(s): Jonathan McGuinness, David Bouchier-Hayes, J Mark Redmond; Dublin, IrelandDiscussant: Vivek Rao

07:48 a.m.
Bio-CABG, Not Only Arteriogenesis but Also a 'Bypass' Surgery, to Expand the Surgical Arena in the Era of Drug Eluting Stents --- a Pre-Clinical Study
Speaker(s): Kiyoaki Takaba, Shintaro Nemoto, Yoshiaki Saji, Chunli Jiang, Tadashi Ikeda, Takashi Azuma, Shinichi Urayama, Sadami Tstutsumi, Yasuhiko Tabata, Masashi Komeda; Kyoto, JapanDiscussant: Todd K. Rosengart

08:00 a.m.
An Egr-1 'Master Switch' for Arteriogenesis and Collateral Vessel Formation: Histologic and Perfusion Studies in Wild Type and Egr-1 Knockout Animals
Speaker(s): Todd K Rosengart, Sorin Sarateanu, McGregor Leslie, James T Beckman, Retuerto A Mauricio, Paul Schalch, JoAnn Carbray, Gerald Patejunas; Evanston, ILDiscussant: Frank W. Sellke

08:12 a.m.
Enhanced Angiogenesis and LV Function with Multimodal Cell-Based Gene Therapy
Speaker(s): Terrence M Yau, Guangming Li, Yaoguang Zhang, Richard D Weisel, Ren-Ke Li; Toronto, ON, CanadaDiscussant: Robert C. Robbins

08:24 a.m.
Stromal Cell-Derived Factor-1a Gene Therapy Improves Endothelial Progenitor Cells Mobilization, Myocardial Neovascularization and Cardiac Function in Chronic Myocardial Infarction
Speaker(s): Yao Liang Tang, Kepin Qian, Lepin Shen, Vinay Badhwar, M Ian Phillips; St. Petersburg, FL, Tampa, FLDiscussant: Y. Joseph Woo

08:36 a.m.
Analysis of TLR4 in Myocardial Ischemia-Reperfusion Injury
Speaker(s): Ani J Fleisig, Christine L Rothnie, Denise J Spring, Erzsebet Toth, Matthew L Agnew, Timothy H Pohlman, Edward D Verrier; Seattle, WADiscussant: Friedhelm Beyersdorf

08:48 a.m.
Impact of Antioxidative Treatment on Myocardial Nuclear Factor Kappa-B Regulation in Patients Subjected to CABG
Speaker(s): Uwe M Fischer, Paschalis Tossios, Albert Antonyan, Reza Raji, Hans Joachim Geissler, Wilhelm Bloch, Uwe Mehlhorn; Cologne, GermanyDiscussant: John S. Ikonomidis



GENERAL THORACIC FORUM SESSION

07:00 a.m.
Promoter Hypermethylation of the hMLH1 Gene, Protein Expression of hMLH1 and MSH2 Genes in Resected Esophageal Carcinoma
Speaker(s): Ching Tzao, Han-Hsuei Hsu, Yi-Ching Wang; Taipei, Taiwan, Republic of ChinaDiscussant: Stephen C. Yang

07:12 a.m.
Selective Decrease in the DNA Base Excision Repair Pathway in Squamous Cell Cancer of the Esophagus
Speaker(s): Pramod N Bonde, Daquing Gao, Lei Chen, Apoorv Broor, Guy Marti, Mark Ferguson, Mark Duncan, John W Harmon, Chiming Wei; Baltimore, MDDiscussant: David H. Harpole, Jr.

07:24 a.m.
WNT Inhibitory Factor-1 is Silenced by Promoter Methylation in Human Lung Cancer
Speaker(s): Julien Mazieres, Biao He, Zhidong Xu, Liang You, David Jablons; San Francisco, CADiscussant: Thomas A. D'Amico

07:36 a.m.
A Novel Technique for Resection of Subcentimeter Pulmonary Nodules Combining Radiotracer Localization with 1318-nm Nd:YAG Laser Excision
Speaker(s): Brendon M Stiles, Talissa A Altes, Patrice K Rehm, Brian M Trotta, Anthony J Herring, Juan Olazagasti, Bijoy Kundu, Mark B Williams, Thomas M Daniel; Charlottesville, VADiscussant: Robert J. McKenna

07:48 a.m.
New Clinically Relevant Model of Gastroesophageal Reflux Leading to Barrett's Metaplasia and Malignant Transformation in Lower Esophagus
Speaker(s): Pramod N Bonde, Carlos Menezes, Zarina Bell, Christine Swarbrick, James Sloan, Sidney Mirvish, Tracy Robson, Stephanie McKeown, Charles Campbell, James A McGuigan; Belfast, UK, Omaha, NE, Baltimore, MDDiscussant: Nasser K. Altorki

08:00 a.m.
Depletion of DNA Methyltransferase (DNMT)1, and/or DNMT3b Mediates Growth Arrest and Apoptosis in Cultured Thoracic Malignancies
Speaker(s): Edmund S Kassis, Ming Zhao, Julie A Hong, G Aaron Chen, Dao M Nguyen, David S Schrump; Bethesda, MDDiscussant: David R. Jones

08:12 a.m.
Prognostic Implication of Aberrant Promoter Hypermethylation of CpG Islands in Adenocarcinoma of the Lung
Speaker(s): Young T Kim, Sun J Park, Seung H Lee, Hee J Kang, Curi Ann, Chang H Kang, Sook W Sung, Joo H Kim; Seoul, South Korea, Gyenggi-do, South KoreaDiscussant: David S. Schrump

08:24 a.m.
Chronic Aspiration of Gastric Contents Contributes to Accelerated Pulmonary Allograft Dysfunction in a Model of Rat Lung Transplantation
Speaker(s): Matthew G Hartwig, Bin Li, James Z Appel III, Chong-Chao Hsieh, Shu S Lin, William Parker, R Duane Davis; Durham, NCDiscussant: Raphael Bueno

08:36 a.m.
Inhibition of PI3K/Akt and Histone Deacetylase Activity Induces Apoptosis in Non-Small Cell Lung Cancer In Vitro and In Vivo
Speaker(s): Brian K Rundall, Chadrick E Denlinger, David R Jones; Charlottesville, VADiscussant: David H. Harpole, Jr.

08:48 a.m.
Patency of Airway Bypass Stents is Prolonged With Use of Drug Eluting Stents
Speaker(s): Cliff K Choong, Loc Phan, Patrick Massetti, Fabio J Haddad, Edmund J Roschak, Joel D Cooper; St Louis, MO, Mountain View, CADiscussant: Steven J. Mentzer



SCIENTIFIC SESSION

09:00 a.m.
The Fate of the Distal Aorta after Repair of Acute Type A Dissection
Speaker(s): James C Halstead, Matthias Meier, David Spielvogel, Carol Bodian, Michael Wurm, Rohit Shahani, Randall B Griepp; New York, NYDiscussant: Axel Haverich

09:20 a.m.
Aspirin Resistance Provokes Early Graft Failure in Veins with Poor Endothelial Integrity After Off-Pump Coronary Artery Bypass
Speaker(s): Robert S Poston, Jr., Junyan Gu, Charles White, Marc Gibber, Jeffrey Manchio, Eric Christenson, Bartley P Griffith; Baltimore, MDDiscussant: Steven F. Bolling

09:40 a.m.
The Extracardiac Conduit Fontan Operation Using Minimal Approach Extracorporeal Circulation: Short and Long Term Outcomes
Speaker(s): Ed Petrossian, V. Mohan Reddy, Kathryn K. Collins, Casey B. Culbertson, Malcolm J. MacDonald, John J. Lamberti, Olaf Reinhartz, Richard D. Mainwaring, Sunil P. Malhotra, Sam Suleman, Frank L. Hanley; Stanford, CADiscussant: Marshall L. Jacobs

10:45 a.m.
Effect of Patient and Prosthesis Size on Operative Mortality After Aortic Valve Replacement
Speaker(s): Charles R Bridges, Joseph C Cleveland, Edward B Savage, James S Gammie, Sean M O'Brien, Fred H Edwards, Elizabeth R Delong, Eric D Peterson, Frederick L Grover; Philadelphia, PA, Denver, CO, Chicago, IL, Baltimore, MD, Durham, NC, Jacksonville, FLDiscussant: George T. Christakis

11:05 a.m.
Predictors of Operative Morbidity and Mortality in the National Emphysema Treatment Trial
Speaker(s): Keith S Naunheim, Douglas E Wood, Mark J Krasna, Mark E Ginsburg, Malcolm M DeCamp, Robert J McKenna, Gerard J Criner, Eric A Hoffman, Alice Sternberg, Claude Deschamps; St. Louis, MO, Seattle, WA, Baltimore, MD, New York, NY, Boston, MA, Los Angeles, CA, Philadelphia, PA, Iowa City, IA, Rochester, MNDiscussant: Joel D. Cooper



ADDRESS BY HONORED SPEAKER

11:45 a.m.
Cardiac Regeneration
Speaker(s): Richard D. Weisel, M.D



SIMULTANEOUS SCIENTIFIC SESSION – CONGENITAL HEART DISEASE

2:00 p.m.
The Left Ventricle that Requires Training by Pulmonary Artery Banding Prior to Double Switch Procedure for Congenitally Corrected Transposition of the Great Arteries is at Risk of Late Dysfunction
Speaker(s): David W Quinn, Simon P McGuirk, Oliver Stumper, Joseph V de Giovanni, Paul Miller, Rami Dhillon, John G Wright, David J Barron, William J Brawn; Birmingham, UKDiscussant: Roger B. B. Mee

2:20 p.m.
Parental Assessment of Intermediate Outcomes Following Fontan in the Current Era
Speaker(s): Michael E Mitchell, Richard F Ittenbach, J William Gaynor, Gil Wernovsky, Susan Nicolson, Thomas L Spray; Louisville, KY, Philadelphia, PADiscussant: William G. Williams

2:40 p.m.
Early Failure of the Freestyle Porcine Valve in the Right Ventricular Outflow Tract of Children with Congenital Heart Disease
Speaker(s): Jeff L Myers, Jamie Dorotan, Matthew Harper, Robert J Ascuitto, Nancy J Ross-Ascuitto, Serafin Y Deleon; New Orleans, LADiscussant: Kirk R. Kanter

3:00 p.m.
Capillary Leak Syndrome after Cardiopulmonary Bypass in Newborns: Does It Exist?
Speaker(s): Peter Tassani, Hubert Schad, Christian Schreiber, Francesco Zaccaria, Felix Haas, Hansjörg Mössinger, Marie - Christine Seghaye, Rüdiger Lange; München, Germany, Utrecht, Netherlands, Aachen, GermanyDiscussant: Jeffrey M. Pearl

3:55 p.m.
Single Ventricle Palliation for High-Risk Neonates: The Emergence of an Alternative Hybrid Stage I Strategy
Speaker(s): Emile A Bacha, Suanne Daves, Joanne P Starr, Ra-id Abdulla, Mehmet Gulecyuz, Peter Koenig, Ermerio Alboliras, Qi-Ling Cao, Satinder Sandhu, Ziyad M Hijazi; Chicago, ILDiscussant: Tom R. Karl

4:15 p.m.
Elective Rapid Re-Training of the Deconditioned Left Ventricle After the Arterial Switch Operation with a Left Ventricular Assist Device
Speaker(s): Nelson Alphonso, Rohayati Taib, Rafael Guerrero, David Michael McMullan, Yves d'Udekem, Dan Penny, Christian Brizard; Melbourne, AustraliaDiscussant: Brian W. Duncan

4:35 p.m.
Surgical Management of Coronary Artery Arising from the Wrong Coronary Sinus, Using Standard and Novel Approaches
Speaker(s): Rajeev Gulati, Vadiyala Mohan Reddy, Casey Culbertson, Gregory Helton, Sam Suleman, Frank L Hanley; Stanford and Oakland, CADiscussant: James Jaggers



SIMULTANEOUS SCIENTIFIC SESSION – ADULT CARDIAC SURGERY

2:00 p.m.
Influence of Patient Characteristics and Arterial Grafting on Freedom from Coronary Reoperation
Speaker(s): Joseph F Sabik III, Eugene H Blackstone, A Marc Gillinov, Michael K Banbury, Nicholas G Smedira, Bruce W Lytle; Cleveland, OHDiscussant: Craig R. Smith

2:20 p.m.
Trial Application of a New Modality to Reduce Neurocognitive Dysfunction Following Cardiopulmonary Bypass - Results of a Prospective Randomised Double-Blind Study
Speaker(s): Joseph Alex, Gerard Laden, Kenneth Flowers, Alex RJ Cale, Sean Bennett, Levent Guvendik, Peter T McCollum, Steven C Griffin; Hull, UKDiscussant: William A. Baumgartner

2:40 p.m.
A Comparison of Outcomes of Mitral Valve Repair for Anterior and Posterior Leaflet Prolapse Due to Degenerative Disease
Speaker(s): Tirone E David, Joan Ivanov, Susan Armstrong, Debbie Christie; Toronto, ON, CanadaDiscussant: Friedrich W. Mohr

3:35 p.m.
Surgical Ventricular Remodeling For Multi-Territory Myocardial Infarction: Defining A New Patient Population
Speaker(s): Nishant D Patel, Christopher J Barreiro, Michele Waldron, Torin P Fitton, Jason A Williams, Pramod Bonde, John V Conte; Baltimore, MDDiscussant: Lorenzo A. Menicanti

3:55 p.m.
The Cox-Maze Procedure in Mitral Valve Disease: Predictors of Failure
Speaker(s): A Marc Gillinov, Patrick M McCarthy, Eugene H Blackstone, Jeevanantham Rajeswaran, Jon Sirak, Gosta Pettersson, Joseph F Sabik III, Lars G Svensson, Delos M Cosgrove; Cleveland, OHDiscussant: Ralph J. Damiano, Jr.

4:15 p.m.
Single Cross Clamp Improves Six Month Cognitive Outcome in High Risk Coronary Bypass Patients
Speaker(s): John W Hammon, David A Stump, John E Butterworth, Kashemi Rorie, Dwight D Deal, Edward A Kincaid, Neal D Kon; Winston-Salem, NCDiscussant: Antonio M. Calafiore

4:35 p.m.
Edwards Perimount Magna Bioprosthesis: A Stented Valve with Stentless Performance?
Speaker(s): Pasquale Totaro, Nello Degno, Afzal Zaidi, Aprim Youhana, Vincenzo Argano; Swansea, UKDiscussant: Neal D. Kon



SIMULTANEOUS SCIENTIFIC SESSION – GENERAL THORACIC SURGERY

2:00 p.m.
Modified Reperfusion in Clinical Lung Transplantation: The Result of 100 Consecutive Cases
Speaker(s): Gabriel T Schnickel, David J Ross, Ali Shefizadeh, Hillel Laks, Ramin Beygui, Joseph Lynch, Abbas Ardehali; Los Angeles, CADiscussant: Wickii T. Vigneswaran

2:20 p.m.
Recurrence Prediction in Thymic Tumors: Importance of Invasion, WHO Histology and Size
Speaker(s): Cameron D Wright, John C Wain, Daniel R Wong, Dean M Donahue, Henning A Gaissert, Hermes C Grillo, Douglas J Mathisen; Boston, MADiscussant: Frank C. Detterback

2:40 p.m.
Long-Term Results After Carinal Resection for Carcinoma: Does the Benefit Warrant the Risk?
Speaker(s): Marc de Perrot, Elie Fadel, Olaf Mercier, Sacha Mussot, Alain Chapelier, Philippe Dartevelle; Le Plessis-Robinson, Paris, FranceDiscussant: Douglas Mathisen

3:00 p.m.
Surgical Treatment of Tumors of the Proximal Stomach with Involvement of the Distal Esophagus: a 26-Year Experience with Siewert Type III Tumors
Speaker(s): K Robert Shen, Stephen D Cassivi, Claude Deschamps, Mark S Allen, Francis C Nichols III, Peter C Pairolero; Rochester, MNDiscussant: Nasser K. Altorki

4:15 p.m.
Surgical Results for Bronchiectasis Based on Hemodynamic and Morphological Classifications
Speaker(s): Khaled M al-Kattan, Waseem M Hajjar, Mohamed A Essa, Mahmoud H Ashour; Riyadh, Saudi Arabia, Riyadh, Saudi ArabiaDiscussant: L. Penfield Faber

4:35 p.m.
Short-Term and Long-Term Results of Pneumonectomy for Lung cancer in the Elderly
Speaker(s): Andrea Zuin, Federico Rea, Giuseppe Marulli, Tobia Gobbi, Monica Loy, Paolo Feltracco, Francesco Sartori; Padua, ItalyDiscussant: Eric Vallieres

4:55 p.m.
The Pattern of Lymph Node Involvement Influences Outcome After Extrapleural Pneumonectomy for Malignant Pleural Mesothelioma
Speaker(s): John G Edwards, Duncan Stewart, Antonio Martin-Ucar, Salli Muller, Cathy Richards, David Waller; Leicester, UKDiscussant: Raja M. Flores